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Home page > Members > Mayeul COLLOT

Mayeul COLLOT

Chargé de recherche (CR2) CNRS

Biophotonics Team

Office/Room : E 004-E 018

Telephone :(+33) +33 (0)3 68 85 42 66

E-Mail : mayeul.collot unistra.fr

 

Dr. Mayeul Collot

Chargé de recherches CNRS (CNRS researcher)

E-mail: mayeul.collot unistra.fr

Room : E 004 – E 018

Tel : (+33) (0)3 68 85 42 66

 

Research

My research focuses on the development of molecular and nanostructured fluorescent probes based on different systems, which provide efficient fluorescent turn-on effects or spectral changes upon detection of cellular events (variation of pH, calcium concentration, reductive environment, ligand/receptor interaction, etc). I mainly developed calcium,1, 2, 3 pH4 and plasma membrane probes5 but I am also involved in project aiming at developing nano-sensors based on nanoparticles6 and new functionalizable polymeric fluorescent nanoparticles for bio-imaging and theranostic.7

 

Education/Career

I started studying biology and chemistry at the Université Pierre & Marie Curie (Paris VI) where I finally graduated in molecular chemistry. I started a PhD at the École Normale Supérieure (ENS) de Paris in 2004 on carbohydrate medicinal chemistry, more specifically in the synthesis of oligosaccharides. In 2008 I joined the Pr. Seeberger’s group as a postdoc (ETH Zürich and Max Planck Institute Berlin) where I worked on the automated synthesis of Glycocsaminoglycans and on multivalent carbohydrates systems. In 2010 I went back to Paris where I changed the topic of my research and where I started developing fluorescent probes and nanostructured sensors. In 2013, I obtained a CNRS researcher position in Strasbourg.

 

(1)     Collot, M.; Ponsot, F.; Klymchenko, A. S. Chem. Commun. 2017, in press.

(2)     Collot, M.; Wilms, C. D.; Bentkhayet, A.; Marcaggi, P.; Couchman, K.; Charpak, S.; Dieudonné, S.; Häusser, M.; Feltz, A.; Mallet, J.-M. eLife 2015, 4, e05808.

(3)     Collot, M.; Loukou, C.; Yakovlev, A. V.; Wilms, C. D.; Li, D.; Evrard, A.; Zamaleeva, A.; Bourdieu, L.; Leger, J.-F.; Ropert, N.; Eilers, J.; Oheim, M.; Feltz, A.; Mallet, J.-M. J. Am. Chem. Soc. 2012, 134 (36), 14923–14931.

(4)     Despras, G.; Zamaleeva, A. I.; Dardevet, L.; Tisseyre, C.; Magalhaes, J. G.; Garner, C.; Waard, M. D.; Amigorena, S.; Feltz, A.; Mallet, J.-M.; Collot, M. Chem. Sci. 2015, 6 (10), 5928–5937.

(5)     Collot, M.; Kreder, R.; Tatarets, A. L.; Patsenker, L. D.; Mely, Y.; Klymchenko, A. S. Chem. Commun. 2015, 51 (96), 17136–17139.

(6)     Attia, M. F.; Dieng, S. M.; Collot, M.; Klymchenko, A. S.; Bouillot, C.; Serra, C. A.; Schmutz, M.; Er-Rafik, M.; Vandamme, T. F.; Anton, N. Macromol. Biosci. 2017.

(7)     Zamaleeva, A. I.; Collot, M.; Bahembera, E.; Tisseyre, C.; Rostaing, P.; Yakovlev, A. V.; Oheim, M.; de Waard, M.; Mallet, J.-M.; Feltz, A. Nano Lett. 2014, 14 (6), 2994–3001.