Laboratoire de Biophotonique et Pharmacologie


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Professeur (PRCE2) UNISTRA

Directeur d'unité

Equipe Biophotonique des interactions moléculaires et cellulaires

Bureau/Salle : E10-E026

Telephone :(+33) +33 (0) 3 68 85 42 63

Courriel : yves.mely



282. K. TROFYMCHUK, A. REISCH, P. DIDIER, F. FRAS, P. GILLIOT, Y. MELY, & A.S. KLYMCHENKO. Giant light harvesting nano-antenna for single molecule detection at ambient light. Nature Photonics. 2017. IF 31.17

281. K. PYRSHEV, S.O. YESYLEVSKYY, Y. MELY, A.P. DEMCHENKO, & KLYMCHENKO, A.S. Caspase-3 activation decreases lipid order in the outer plasma membrane leaflet during apoptosis : a fluorescent probe study. Biochim Biophys Acta- Biomembranes, 2017, 1859, 2123-2132. IF 3.50

280. V.G. PIVOVARENKO, O. BUGERA, N. HUMBERT, A.S. KLYMCHENKO, & Y. MELY. A toolbox of chromones and quinolones for measuring a wide range of ATP concentrations. Chemistry, 2017, 23, 11927-11934. IF 5.32.

279. O. DUKHNO, F. PRZYBILLA, M. COLLOT, A. KLYMCHENKO, V. PIVOVARENKO, M. BUCHNER, V. MUHR, T. HIRSCH, & Y. MELY. Quantitative assessment of energy transfer in upconverting nanoparticles grafted with organic dyes. Nanoscale. 2017, 9, 11994-12004. IF 7.37

278. N. VOSNAKIS, M. KOCH, E. SCHEER, P. KESSLER, Y. MELY, P. DIDIER, & L. TORA. Coactivators and general transcription factors have two dynamic populations dependent on transcription. Embo J., 2017, 36, 2710-2725. IF 9.79

277. R. BOUCHAALA, N. ANTON, H. ANTON, T. VANDAMME, J. VERMOT, D. SMAIL, Y. MELY. & A.S. KLYMCHENKO. Light-triggered release from dye-loaded fluorescent lipid nanocarriers in vitro and in vivo. Colloids and Surfaces B : Biointerfaces 2017, 156, 414-421. IF 3.89

276. W. ASHRAF, A. IBRAHIM, M. ALHOSIN, L. ZAAYTER, K. OUARARHNI, C. PAPIN, T. AHMED, A. HAMICHE, Y. MELY, C. BRONNER, & M. MOUSLI. The epigenetic integrator UHRF1 : on the road to become a universal biomarker for cancer. Oncotarget. 2017, 8, 51946-51962 IF 5.4

275.  D. FRATH, P. DIDIER, Y. MELY, J. MASSUE, G. ULRICH. Vectorization and Intracellular Distribution of a Two Photon-Absorbing, Near Infra-Red (NIR) Emitting π-Extended Boranil Dye. ChemPhotoChem., 2017, 1, 109-112.

274. A. GHOSE, O. MALTSEV, N. HUMBERT, L. HINTERMANN, Y. ARNTZ, P. NAUMOV,  Y. MELY, & P. DIDIER. Oxyluciferin Derivatives : A Toolbox of Environment-Sensitive Fluorescence Probes for Molecular and Cellular Applications. J. Phys. Chem. B., 2017, 121, 1566-1575. IF 3.18

273.  V. KILIN, K. GAVVALA, N.P. BARTHES, B.Y. MICHEL, D. SHIN, C. BOUDIER, O. MAUFFRET, V. YASHCHUK, M. MOUSLI, M. RUFF, F. GRANGER, S. EILER, C. BRONNER, Y. TOR, A. BURGER, & Y. MELY. Dynamics of methylated cytosine flipping by UHRF1. J. Am. Chem. Soc. 2017, 139, 2520-2528. IF 13.86

272. L. PETRIZZA, M. COLLOT, L. RICHERT. Y. MELY, L. PRODI, & A.S. KLYMCHENKO. Dye-doped silica nanoparticle probes for fluorescence lifetime imaging of reductive environment in living cells. RSC Adv., 2016, 6, 104164. IF 3.29

271. I. LYSOVA, H. ANTON, I. DMITRUK, & Y. MELY. Tuning luminescent properties of CdSe nanoclusters by phosphine surface passivation. Methods Appl. Fluoresc. 2016, 4, 044009. IF 2.43

270. N.P.F. BARTHES, K. GAVVALA, D. BONHOMME, A.S. DABERT-GAY, D. DEBAYLE, Y. MELY, B.Y. MICHEL, & A. BURGER. Design and development of a two-color emissive FRET pair based on a photostable fluorescent deoxyuridine donor presenting mega-Stokes shifts. J. Org. Chem., 2016, 81, 10733-10741. IF 4.79

269. J.L. DARLIX, H. de ROCQUIGNY, & Y. MELY. The multiple roles of the nucleocapsid in retroviral RNA conversion into proviral DNA by reverse transcriptase. Biochem. Soc. Trans., 2016, 44, 1427-1440. IF 3.59

268. K. GAVVALA, N.P.F. BARTHES, D. BONHOMME, A.S. DABERT-GAY, D. DEBAYLE, B.Y. MICHEL, A. BURGER, & Y. MELY. A Turn-On Dual Emissive Nucleobase Sensitive to Mismatches and Duplex Conformational Changes. RSC Adv., 2016, 6, 87142-87146. IF 3.29

267. H. EL MEKDAD, E. BOUTANT, H. KARNIB, M.E. BIEDMA, K.K SHARMA, I. MALYTSKA, G. LAUMOND, M. ROY, E. REAL, J.C. PAILLART, C. MOOG, J.L. DARLIX, Y. MELY, & H. de ROCQUIGNY. Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling. Retrovirology, 2016, 13, 54. IF 4.19

266. L. RICHERT, N. HUMBERT, E. LARQUET, Y. GIRERD-CHAMBAZ, C. MANIN, F. RONZON, & Y. MELY. Fluorescence correlation spectroscopy as a sensitive and useful tool for revealing potential overlaps between the epitopes of monoclonal antibodies on viral particles. mAbs, 2016, 8, 1235-1244. IF 4.07

265. W. ELGAHER, K. SHARMA, J. HAUPENTHAL, F. SALADINI, M. PIRES, E. REAL, Y. MELY, & R. HARTMANN. Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-Carboxylic Acids as Dual Bacterial RNAP and Viral RT Inhibitors. J. Med. Chem., 2016, 59, 7212-7222. IF 5.59

264. R. BOUCHAALA, L. MERCIER, B. ANDREIUK, Y. MELY, T.F. VANDAMME, N. ANTON, J. GOETZ, & A. KLYMCHENKO. Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice. J. Control. Release, 2016, 236, 57-67. IF 7.44

263. A.N. ZAMOTAIEV, V. SHVADCHAK, T. SYCH, N. MELNYCHUK, D. YUSHCHENKO, Y. MELY, & V.G. PIVOVARENKO. Environment-Sensitive Quinolone Demonstrating Long-Lived Fluorescence and Unusually Slow Excited-State Intramolecular Proton Transfer Kinetics. Methods Appl. Fluoresc. 2016, 4, 034004. IF 2.43

262. M. SHOLOKH, R. IMPROTA, M. MORI, R. SHARMA, C. KENFACK, D. SHIN, K. VOLZ, R.H. STOTE, O.A. ZAPOROZHETS, M. BOTTA, Y. TOR, & Y. MELY. Tautomers of a Fluorescent G Surrogate and Their Distinct Photophysics Provide Additional Information Channels. Angew. Chem. Int. Ed. Engl. 2016, 55, 7974-7978. IF 10.42

261. I. SHULOV, Y. ARNTZ, Y. MELY, V.G. PIVOVARENKO, & A.S. KLYMCHENKO. Non-coordinating anions assemble cyanine amphiphiles into ultra-small fluorescent nanoparticles. Chem Comm. 2016, 52, 7962-7965. IF 6.57

260. D. KOSCHUT, L. RICHERT, GIUSEPPINA P., H.H. NIEMANN, Y. MELY, & V.ORIAN-ROUSSEAU. Live Cell Imaging Shows Hepatocyte Growth Factor-induced Met Dimerization. Biochim Biophys Acta. Mol Cell Res, 2016, 1863, 1552-1558. IF 5.13

259. D. DESPLANCQ, G. FREUND, S. CONIC, A-P. SIBLER, P. DIDIER, A. STOESSEL, M. OULAD-ABDELGHANI, M. VIGNERON, J. WAGNER, Y. MELY, B. CHATTON, L. TORA, & E. WEISS. Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells. Exp. Cell Res. 2016, 342, 45-58. IF 3.38